ITGA5 Antikörper (AA 981-1049) (HRP)
Kurzübersicht für ITGA5 Antikörper (AA 981-1049) (HRP) (ABIN7091271)
Target
Alle ITGA5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 981-1049
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Kreuzreaktivität
- Human, Maus
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Homologie
- Rat,Cow,Sheep,Pig,Horse,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human Integrin alpha 5
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Isotyp
- IgG
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Applikationshinweise
- WB 1:300-5000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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- ITGA5 (Integrin, alpha 5 (ITGA5))
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Andere Bezeichnung
- Integrin alpha 5
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Hintergrund
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Synonyms: Integrin alpha-5 light chain, Alpha 5 beta 1, CD49 antigen-like family member E, CD49e, ECMRVI, Fibronectin Receptor alpha, Fibronectin receptor alpha subunit, Fibronectin receptor, alpha subunit, FNR, FNRA, gpIc/IIa, Integrin alpha 5 (fibronectin receptor alpha), Integrin alpha 5, Integrin alpha F, Integrin alpha-5, Integrin alpha-F, Integrin, alpha 5 (fibronectin receptor, alpha polypeptide), ITGA5, Very late Activation Antigen 5, Very Late Activation Protein 5 alpha, Very late activation protein 5, alpha subunit, VLA5, VLA5A, ITA5_HUMAN, Integrin α5, Integrin-α5.
Background: CD49e is the integrin alpha 5 chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 5 undergoes post translational cleavage in the extracellular domain to yield disulfide linked light and heavy chains that join with beta 1 to form a fibronectin receptor that is known variously: in lymphocytes as very late (activation) antigen 5 (VLA5), in platelets as glycoprotein IcIIa, and in fibroblasts as extracellular matrix receptor 6 (ECMVI). In addition to adhesion, integrins are known to participate in cell surface mediated signalling.
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Gen-ID
- 3678
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UniProt
- P08648
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Pathways
- Integrin Complex
Target
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