Importin 9 Antikörper (AA 1-388)

Produktnummer ABIN7091241

Dieser Maus Monoklonal Antikörper detektiert spezifisch Importin 9 in WB, IF, IHC (p) und IHC (fro). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Importin 9 Antikörper (AA 1-388) (ABIN7091241)

Target: Importin 9 (IPO9)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Importin 9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: B5F6

Produktdetails anti-Importin 9 Antikörper

Bindungsspezifität: AA 1-388

Verwendungszweck: RANBP9 Monoclonal Antibody

Homologie: Human

Immunogen: Recombinant human RANBP9 between 1-388 amino acids.

Anwendungsinformationen

Applikationshinweise: WB(WB=1:500-4000), IHC-P(IHC-P=1:25), IHC-F(IHC-F=1:25), IF(IF=1:25)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu Importin 9

Target: Importin 9 (IPO9)

Andere Bezeichnung: RANBP9

Hintergrund:

Synonyms: RANB9_HUMAN, Ran-binding protein 9, RanBP9, BPM-L, BPM90, Ran-binding protein M, RanBPM, RanBP7.

Background: May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA.

Gen-ID: 10048

UniProt: Q96S59

Pathways: Protein targeting to Nucleus