GDF11 Antikörper

Produktnummer ABIN7091177

Dieses Anti-GDF11-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von GDF11 in WB. Geeignet für Human.

Kurzübersicht für GDF11 Antikörper (ABIN7091177)

Target: GDF11 (Growth Differentiation Factor 11 (GDF11))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GDF11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: C4F5

Produktdetails anti-GDF11 Antikörper

Homologie: Human

Immunogen: Recombinant human GDF11.

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu GDF11

Target: GDF11 (Growth Differentiation Factor 11 (GDF11))

Andere Bezeichnung: BMP11

Hintergrund:

Synonyms: GDF11, BMP 11, Bone morphogenetic protein 11, GDF 11, Growth differentiation factor 11, Growth/differentiation factor 11, GDF11_HUMAN.

Background: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis, the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses.

Gen-ID: 10220

UniProt: O95390