XRN1 Antikörper (AA 1455-1706)

Produktnummer ABIN7090717

Der Maus Monoklonal Anti-XRN1-Antikörper wurde für WB validiert. Er ist geeignet, XRN1 in Proben von Human zu detektieren.

Kurzübersicht für XRN1 Antikörper (AA 1455-1706) (ABIN7090717)

Target: XRN1 (5'-3' Exoribonuclease 1 (XRN1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser XRN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: F12D4

Produktdetails anti-XRN1 Antikörper

Bindungsspezifität: AA 1455-1706

Kreuzreaktivität: Human

Homologie: Mouse

Aufreinigung: Purified by Protein G.

Immunogen: Recombinant human XRN1 between1455-1706 amino acids.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu XRN1

Target: XRN1 (5'-3' Exoribonuclease 1 (XRN1))

Andere Bezeichnung: XRN1

Hintergrund:

Synonyms: XRN1_HUMAN, Dhm2, mXRN1, SEP1, Strand-exchange protein 1 homolog, 5'-3' exoribonuclease 1.

Background: Lamins are type V intermediate filament proteins and are grouped into constitutively expressed B-type lamins and developmentally regulated A-type lamins. Lamin-binding proteins in the nuclear lamina and the nuclear interior include several protein families and/or types of proteins in higher eukaryotes such as the inner nuclear membrane proteins, lamin B receptor, emerin, MANI, three isoforms of lamina-associated polypeptide 1 (LAP 1), and several isoforms of LAP 2. Up to six LAP 2 isoforms derive from a single gene by alternative splicing in mammals and various isoforms have been described in Xenopus. The best characterized LAP2 isoforms are the inner nuclear membrane protein LAP 2 beta and the nucleoplasmic protein LAP 2 alpha, which are identical in their N-terminal 187-amino acid constant region but differ in their C termini. LAP 2 alpha specifically interacts with A-type lamins within the nuclear interior as part of a detergent- and salt-resistant nucleoskeletal structure.

Gen-ID: 54464

UniProt: Q8IZH2