TRIP10 Antikörper (AA 151-250)

Produktnummer ABIN706121

Der Kaninchen Polyklonal Anti-TRIP10-Antikörper wurde für WB, ELISA, IF (cc), IF (p), IHC (p) und IHC (fro) validiert. Er ist geeignet, TRIP10 in Proben von Maus zu detektieren.

Kurzübersicht für TRIP10 Antikörper (AA 151-250) (ABIN706121)

Target: TRIP10 (Thyroid Hormone Receptor Interactor 10 (TRIP10))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIP10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-TRIP10 Antikörper

Bindungsspezifität: AA 151-250

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Cip4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu TRIP10

Target: TRIP10 (Thyroid Hormone Receptor Interactor 10 (TRIP10))

Andere Bezeichnung: Cip4

Hintergrund:

Synonyms: Cdc42 interacting protein 4, Cdc42 interaction protein 4 long isoform, Cdc42-interacting protein 4, Cip 4, CIP4_HUMAN, DCIP4, hSTP, Protein Felic, Salt tolerant protein, Salt tolerator, STOT, STP, Thyroid hormone receptor interactor 10, Thyroid receptor interacting protein 10, Thyroid receptor-interacting protein 10, TR-interacting protein 10, TRIP 10, TRIP-10, trip10, Truncated Cdc42 interaction protein 4.

Background: Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.

Gen-ID: 9322