TBL1XR1 Antikörper (AA 231-330) (HRP)

Produktnummer ABIN705440

Der Kaninchen Polyklonal Anti-TBL1XR1-Antikörper wurde für WB, ELISA, IHC (p) und IHC (fro) validiert. Er ist geeignet, TBL1XR1 in Proben von Maus und Ratte zu detektieren.

Kurzübersicht für TBL1XR1 Antikörper (AA 231-330) (HRP) (ABIN705440)

Target: TBL1XR1 (Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TBL1XR1 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-TBL1XR1 Antikörper (HRP)

Bindungsspezifität: AA 231-330

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Pig,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TBLR1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu TBL1XR1

Target: TBL1XR1 (Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1))

Andere Bezeichnung: TBLR1

Hintergrund:

Synonyms: C21, DC42, IRA1, TBLR1, F-box-like/WD repeat-containing protein TBL1XR1, Nuclear receptor corepressor/HDAC3 complex subunit TBLR1, TBL1-related protein 1, Transducin beta-like 1X-related protein 1, TBL1XR1

Background: F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation.

Gen-ID: 79718

UniProt: Q9BZK7

Pathways: Regulation of Lipid Metabolism by PPARalpha