Der Biotin-konjugierte Maus Monoklonal anti-MHC Class II HLA-DP/DQ/DR Antikörper (Klon IVA12) (ABIN7077536) detektiert spezifisch MHC Class II HLA-DP/DQ/DR in FACS.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
Kurzübersicht für MHC Class II HLA-DP/DQ/DR Antikörper (Biotin) (ABIN7077536)
Target
MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR)
Reaktivität
Human
Wirt
Maus
Klonalität
Monoklonal
Konjugat
Dieser MHC Class II HLA-DP/DQ/DR Antikörper ist konjugiert mit Biotin
Applikation
Flow Cytometry (FACS)
Güteklasse
GMP Grade
Klon
IVA12
Verwendungszweck
Anti-HLA-DR, DP, DQ Biotin Antibody
Produktmerkmale
The clone IVA12 recognizes the shared epitopes of human leukocyte antigen (HLA) class II molecules HLA-DP, HLA-DQ and HLA-DR heterodimeric cell surface glycoproteins comprised of an α (heavy) chain and a β (light) chain. They are expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional antigen presenting cells (APCs). HLA-Class II expressing APCs specifically present antigens recognized by TCR/CD3 complex of CD4+ T cells. Reactive microglia and perivascular cells in multiple sclerosis lesions express all three types of HLA-Class II molecules, whereas microglia in the normal CNS express HLA-DR only.