CD8 alpha Antikörper (mFluor™450)

Produktnummer ABIN7077484

Dieser Maus Monoklonal Antikörper erkennt spezifisch CD8 alpha in FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD8 alpha Antikörper (mFluor™450) (ABIN7077484)

Target: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD8 alpha Antikörper ist konjugiert mit mFluor™450

Applikation: Flow Cytometry (FACS)

Güteklasse: GMP Grade

Klon: SK1

Produktdetails anti-CD8 alpha Antikörper (mFluor™450)

Verwendungszweck: CD8a mFluor450 Antibody

Kreuzreaktivität: Pavian, Schimpanse, Cynomolgus, Green Monkey, Macaca nemestrina, Rhesusaffen, Sooty mangabey (Cercocebus atys)

Produktmerkmale: The clone SK1 specifically binds with a 32-34 kDa type I transmembrane glycoprotein of human cells commonly known as CD8a.  It is a member of immunoglobulin superfamily.  The CD8α forms either a homodimer (2 alpha chains) or a heterodimer with CD8β and is expressed on the surface of cytotoxic T cells, and sub-sets of NK cells, cortical thymocytes, and also on some dendritic cells. CD8 functions as a co-receptor for T cell receptor and specifically binds to class I MHC for antigen recognition and T cell activation. It has the cross-reactive binding affinity with the CD8 cell surface antigen expressing in several non-human primates, including Baboon, Chimpanzee, Cynomolgus and Rhesus.

Aufreinigung: Purified

Reinheit: >95 %

Immunogen: Human peripheral blood T cells

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C, Conjugated antibodies should never be frozen.

Details zu CD8 alpha

Target: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Andere Bezeichnung: CD8a

Gen-ID: 925

NCBI Accession: NM_001768

UniProt: P01732

Pathways: T-Zell Rezeptor Signalweg