CD8 alpha Antikörper (mFluor™510)
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- Target Alle CD8 alpha (CD8A) Antikörper anzeigen
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD8 alpha Antikörper ist konjugiert mit mFluor™510
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Applikation
- Flow Cytometry (FACS)
- Verwendungszweck
- CD8a mFluor500 Antibody
- Kreuzreaktivität
- Pavian, Schimpanse, Cynomolgus, Green Monkey, Macaca nemestrina, Rhesusaffen, Sooty mangabey (Cercocebus atys)
- Produktmerkmale
- The clone SK1 specifically binds with a 32-34 kDa type I transmembrane glycoprotein of human cells commonly known as CD8a. It is a member of immunoglobulin superfamily. The CD8α forms either a homodimer (2 alpha chains) or a heterodimer with CD8β and is expressed on the surface of cytotoxic T cells, and sub-sets of NK cells, cortical thymocytes, and also on some dendritic cells. CD8 functions as a co-receptor for T cell receptor and specifically binds to class I MHC for antigen recognition and T cell activation. It has the cross-reactive binding affinity with the CD8 cell surface antigen expressing in several non-human primates, including Baboon, Chimpanzee, Cynomolgus and Rhesus.
- Aufreinigung
- Purified
- Reinheit
- >95 %
- Güteklasse
- GMP Grade
- Immunogen
- Human peripheral blood T cells
- Klon
- SK1
- Isotyp
- IgG1, kappa
- Top Product
- Discover our top product CD8A Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- 2-8°C, Conjugated antibodies should never be frozen.
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- Target
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
- Andere Bezeichnung
- CD8a (CD8A Produkte)
- Gen-ID
- 925
- NCBI Accession
- NM_001768
- UniProt
- P01732
- Pathways
- T-Zell Rezeptor Signalweg
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