CD1a Antikörper (PE)

Produktnummer ABIN7076789

Dieses Anti-CD1a-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CD1a in FACS. Geeignet für Human.

Kurzübersicht für CD1a Antikörper (PE) (ABIN7076789)

Target: CD1a

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD1a Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Güteklasse: GMP Grade

Klon: OKT6

Produktdetails anti-CD1a Antikörper (PE)

Verwendungszweck: CD1a PE Antibody

Produktmerkmale: The clone OKT6, a mouse monoclonal antibody selectively recognizes 49- kDa type I transmembrane glycoprotein non-covalently associated with β2-microglobulin known as CD1a. The CD1a glycoprotein has structural similarities to MHC class I molecule and plays important role in antigen-presenting mechanism to T-cell receptors present on NK T-cells. It is expressed on cortical double positive and single positive thymocytes, Langerhans cells, and dendritic cells. In addition to antigen presentation NK T-cells, CD1a has been implicated in thymic T cell development. CD1a has been used as a marker for DCs in a range of human tumors and the density of CD1a DC has been associated with clinical outcome in patients with lung, colon, gastric, nasopharyngeal, laryngeal and tongue carcinomas.

Aufreinigung: Purified

Reinheit: >95 %

Immunogen: Human acute lymphoblastic leukemia cells

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C, Conjugated antibodies should never be frozen.

Details zu CD1a

Target: CD1a

Andere Bezeichnung: CD1a

Gen-ID: 909

UniProt: P06126

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process