CD4 Antikörper (FITC)

Produktnummer ABIN7076564

Der Maus Monoklonal Anti-CD4-Antikörper wurde für FACS validiert. Er ist geeignet, CD4 in Proben von Human, Rhesusaffen und Cynomolgus zu detektieren.

Kurzübersicht für CD4 Antikörper (FITC) (ABIN7076564)

Target: CD4

Reaktivität: Human, Rhesusaffen, Cynomolgus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD4 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Güteklasse: GMP Grade (Analyte)

Klon: SK3

Produktdetails anti-CD4 Antikörper (FITC)

Verwendungszweck: CD4 FITC Antibody

Produktmerkmale: The clone SK3, a mouse monoclonal antibody selectively binds with a 55-59kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. CD4 contains four extracellular Ig-like domains (D1-D4). The epitope for SK3 is located within the D3 domain of the protein, which has a structure resembling an Ig variable domain. Expression of CD4 is observed in subsets of T lymphocytes, monocytes, macrophages, and dendritic cells. Through interaction of MHC-II, CD4 facilitates cell-cell interaction, thymic differentiation, and activation of downstream signaling cascades. HIV infection of T-cells is instigated through binding of HIV to CD4. Binding of SK3 antibody blocks HIV infection through CD4 and also blocks the mixed lymphocyte reaction (MLR).

Aufreinigung: Purified

Reinheit: >95 %

Immunogen: Human peripheral blood T cell

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: FC: 5 µL/test We recommend that every lab carries out an initial titration study before running your samples to ensure that the optimal concentration is selected for your application.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.2, 0.09 % Sodium azide and 0.2 % (w/v) BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C, Conjugated antibodies should never be frozen.

Details zu CD4

Target: CD4

Andere Bezeichnung: CD4

Gen-ID: 920

NCBI Accession: NM_000616

UniProt: P01730

Pathways: T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events