Vegf Receptor 3 Antikörper

Produktnummer ABIN7076194

Der Kaninchen Polyklonal anti-Vegf Receptor 3 Antikörper (ABIN7076194) detektiert spezifisch Vegf Receptor 3 in IF, IHC und WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Vegf Receptor 3 Antikörper (ABIN7076194)

Target: Vegf Receptor 3

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Applikation: Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)

Produktdetails

Kreuzreaktivität: Human, Ratte

Aufreinigung: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse VEGF Receptor 3

Anwendungsinformationen

Applikationshinweise: WB (H) 1:500-1:1000, IHC/IF (M,R) 1:400-1:1200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Antigendetails

Target: Vegf Receptor 3

Hintergrund: Vascular endothelial growth factors (VEGFs) are a family of closely related growth factors having a conserved pattern of eight cysteine esidues and sharing common VEGF receptors. VEGFs stimulate the proliferation of endothelial cells, induce angiogenesis, and increase vascular permeability in both large and small vessels. The mitogenic activity of VEGFs appears to be mediated by specific VEGF receptors. VEGF Receptor 3 is one of the five receptor tyrosine kinases (RTKs) (VEGF Receptor 1/Flt1, VEGF Receptor 2/KDR/Flk1, VEGF Receptor 3/Flt4, tie1 and tek/tie2) whose expression is almost exclusively restricted to endothelial cells.

Molekulargewicht: 130 kDa

Gen-ID: 14257

NCBI Accession: NP_032055

UniProt: P35917