UNC13A/Munc13-1 Antikörper

Produktnummer ABIN7076146

Dieses Anti-UNC13A/Munc13-1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von UNC13A/Munc13-1 in WB. Geeignet für Maus und Ratte.

Kurzübersicht für UNC13A/Munc13-1 Antikörper (ABIN7076146)

Target: UNC13A/Munc13-1 (UNC13A) (Unc-13 Homolog A (UNC13A))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UNC13A/Munc13-1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-UNC13A/Munc13-1 Antikörper

Kreuzreaktivität: Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse Munc13-1

Anwendungsinformationen

Applikationshinweise: WB (M,R) 1: 1000-1: 2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu UNC13A/Munc13-1

Target: UNC13A/Munc13-1 (UNC13A) (Unc-13 Homolog A (UNC13A))

Andere Bezeichnung: Munc13-1

Hintergrund: Unc-13 homolog A (C. elegans) is a protein that in humans is encoded by the UNC13A gene.. This gene encodes a member of the UNC13 family. UNC13A plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. It is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool. It is particularly important in most glutamatergic-mediated synapses but not GABA-mediated synapses. It plays a role in dendrite formation by melanocytes and in secretory granule priming in insulin secretion.

Molekulargewicht: 194 kDa

Gen-ID: 382018

NCBI Accession: NP_001025044

UniProt: Q4KUS2

Pathways: Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis