UBR5 Antikörper
Kurzübersicht für UBR5 Antikörper (ABIN7076102)
Target
Alle UBR5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Ratte
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Aufreinigung
- Affinity purification
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Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse EDD
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Applikationshinweise
- IHC/IF (M,R) 1:350-1:700
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- UBR5 (Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5))
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Andere Bezeichnung
- EDD
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Hintergrund
- UBR5, also named as ubiquitin protein ligase E3 component n-reconin5, is a HECT domain-containing protein as a myocardin-binding protein. UBR5 is highly conserved in metazoans, has unique structural features, and has been implicated in regulation of DNA damage response, metabolism, transcription, and apoptosis. Hence, UBR5 is a key regulator of cell signaling relevant to broad areas of cancer biology . The human UBR5 gene has 59 exons, encoding an approximately 10kb mRNA and >300 kDa protein with widespread expression in various cell types.
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Gen-ID
- 70790
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NCBI Accession
- NP_001074828
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UniProt
- Q80TP3
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
Target
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