TTL Antikörper
Kurzübersicht für TTL Antikörper (ABIN7076048)
Target
Alle TTL Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Kreuzreaktivität
- Ratte
-
Aufreinigung
- Affinity purification
-
Immunogen
- Recombinant protein corresponding to Mouse TTL
-
-
-
-
Applikationshinweise
- IHC/IF (M,R) 1:2000-1:4000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- PBS, pH 7.4, 0.02 % sodium azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
-
- TTL (Tubulin tyrosine Ligase (TTL))
-
Andere Bezeichnung
- TTL
-
Hintergrund
- Tubulin-tyrosine ligase (TTL) is the enzyme responsible for the reversible addition of a tyrosine residue at the carboxyl end of alpha-tubulin. TTL forms stable complexes with tubulin and inhibit tubulin polymerization. TTL is frequently suppressed during tumor progression with resulting accumulation of detyrosinated alpha-tubulin in tumor cells. TTL suppression in human cancers is associated with increased tumor aggressiveness.
-
Gen-ID
- 69737
-
NCBI Accession
- NP_081468
-
UniProt
- P38585
-
Pathways
- Regulation of Cell Size
Target
-