TMEM199 Antikörper
Kurzübersicht für TMEM199 Antikörper (ABIN7075998)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Human, Ratte
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant protein corresponding to Mouse TMEM199
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Applikationshinweise
- WB (H,M,R) 1:2000-1:4000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- TMEM199 (Transmembrane Protein 199 (TMEM199))
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Andere Bezeichnung
- TMEM199
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Hintergrund
- TMEM199, also named as C17orf32, is a component of the complex sense antisense architecture (CSAGA).Accessory component of the proton-transporting vacuolar (V)-ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe2+ prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation . May be involved in Golgi homeostasis.
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Molekulargewicht
- 23 kDa
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Gen-ID
- 195040
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NCBI Accession
- NP_954669
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UniProt
- Q5SYH2
Target
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