TEX264 Antikörper

Produktnummer ABIN7075863

Produktdetails anti-TEX264 Antikörper

Target: TEX264 (Testis Expressed 264 (TEX264))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TEX264 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse TEX264

Anwendungsinformationen

Applikationshinweise: WB (M,R) 1:1000-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu TEX264

Target: TEX264 (Testis Expressed 264 (TEX264))

Andere Bezeichnung: TEX264 (TEX264 Produkte)

Synonyme: ZSIG11 antikoerper, TEG-264 antikoerper, testis expressed 264 antikoerper, testis expressed gene 264 antikoerper, TEX264 antikoerper, Tex264 antikoerper

Hintergrund: Major reticulophagy (also called ER-phagy) receptor that acts independently of other candidate reticulophagy receptors to remodel subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover. The ATG8-containing isolation membrane (IM) cradles a tubular segment of TEX264-positive ER near a three-way junction, allowing the formation of a synapse of 2 juxtaposed membranes with trans interaction between the TEX264 and ATG8 proteins. Expansion of the IM would extend the capture of ER, possibly through a 'zipper-like' process involving continued trans TEX264-ATG8 interactions, until poorly understood mechanisms lead to the fission of relevant membranes and, ultimately, autophagosomal membrane closure.

Molekulargewicht: 34 kDa

UniProt: Q99LS5