SUPT3H/SPT3 Antikörper

Produktnummer ABIN7075767

Der Kaninchen Polyklonal Anti-SUPT3H/SPT3-Antikörper wurde für WB, IHC und IF validiert. Er ist geeignet, SUPT3H/SPT3 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für SUPT3H/SPT3 Antikörper (ABIN7075767)

Target: SUPT3H/SPT3 (SUPT3H) (Suppressor of Ty 3 Homolog (SUPT3H))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SUPT3H/SPT3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-SUPT3H/SPT3 Antikörper

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Human SUPT3H

Anwendungsinformationen

Applikationshinweise: WB (H,M,R) 1:500-1:1000, IHC/IF (M,R) 1:500-1:1500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu SUPT3H/SPT3

Target: SUPT3H/SPT3 (SUPT3H) (Suppressor of Ty 3 Homolog (SUPT3H))

Andere Bezeichnung: SUPT3H

Hintergrund: The transcription of many RNA polymerase II-dependent genes requires Spt3, a member of the S. cerevisiae SAGA complex. Transcription from delta sequences, the long terminal repeats that flank yeast Ty elements, requires the yeast SPT3 gene. Spt3 and Spt20 work together to recruit TATA-box binding protein (TBP) to the core promoter allowing TBP to bind to SAGA-dependent promoters. Null mutations in the Spt3 gene cause defects in sporulation, diploid filamentous growth, and haploid invasive growth, indicating that Spt3 has an important role in both mating and development pathways in yeast. At the promoters of some genes including yeast HO, HIS3 and TRP3 genes, Spt3 inhibits binding of TBP, resulting in reduced transcription.

Molekulargewicht: 36 kDa

Gen-ID: 8464

UniProt: O75486