Der Kaninchen Polyklonal Anti-Stabilin 1 Antikörper wurde für WB validiert. Er ist geeignet, Stabilin 1 in Proben von Maus und Ratte zu detektieren. Es ist 1 Publikation verfügbar.
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Lagerung
-20 °C
Chang, Zhong, Xu, Zhang, Guo, Yu, Xu, Han, Han, Lv, Tian: "Multi-modal integration of histopathology and transcriptomics reveals STAB1+ macrophage-associated efferocytosis as a suppressive immune mechanism in colon adenocarcinoma." in: Journal of translational medicine, Vol. 23, Issue 1, pp. 1386, (2025) (PubMed).
Target
Stabilin 1 (STAB1)
Andere Bezeichnung
Stabilin1
Hintergrund
Stabilin-1 is a large transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 16 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to endocytose ligands such as low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products.