SMYD2A Antikörper
Kurzübersicht für SMYD2A Antikörper (ABIN7075581)
Target
Alle SMYD2A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Ratte
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant protein corresponding to Mouse SMYD2
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Applikationshinweise
- IHC/IF (M,R) 1:1000-1:4000/1:1000-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- SMYD2A (SET and MYND Domain Containing 2a (SMYD2A))
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Andere Bezeichnung
- KMT3C/SMYD2
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Hintergrund
- Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Has also methyltransferase activity toward non-histone proteins such as p53/TP53 and RB1. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53.
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Gen-ID
- 226830
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NCBI Accession
- NP_081072
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UniProt
- Q8R5A0
Target
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