RUVBL1 Antikörper
Kurzübersicht für RUVBL1 Antikörper (ABIN7075488)
Target
Alle RUVBL1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Human, Ratte
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant protein corresponding to Mouse TIP49A
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Applikationshinweise
- WB (H,M) 1:500-1:1000, IHC/IF (H,R) 1:300-1:600
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- RUVBL1 (RuvB-Like 1 (E. Coli) (RUVBL1))
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Andere Bezeichnung
- TIP49A
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Hintergrund
- RUVBL1 is a member of the AAA (ATPase associated with diverse cellular activities) family of proteins that is associated with several chromatin-remodelling complexes and has important roles in transcriptional regulation, the DNA damage response, telomerase activity, snoRNP assembly, cellular transformation and cancer metastasis[PMID: 21617703]. It consists of 456 amino acids (50 kDa) and interacts with TATA-binding protein (TBP), which is a central component for transcriptional regulation by forming complexes with various transcription regulators. RUVBL1 is a component of a large nuclear protein complex, possibly the RNA polymerase II holoenzyme.
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Molekulargewicht
- 55 kDa
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Gen-ID
- 56505
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NCBI Accession
- NP_062659
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UniProt
- P60122
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Pathways
- Telomere Maintenance
Target
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