Der Kaninchen Polyklonal anti-RAB21 Antikörper wird verwendet zum Nachweis von RAB21 in Proben von Human, Ratte und Maus. Er wurde validiert für WB, IHC und IF.
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Lagerung
-20 °C
Target
RAB21
(RAB21, Member RAS Oncogene Family (RAB21))
Andere Bezeichnung
RAB21
Hintergrund
RAB21 is a member of a subfamily of small GTP-binding protein genes of the Ras superfamily that plays an important role in intracellular vesicular targeting. In non-polarized Caco-2 cells, RAB21 showed a general endoplasmic reticulum (ER)-like localization, while in polarized cells, RAB21 localized to apical vesicles. RAB21 has been shown to associate with integrin subunits and to be important for receptor entry into cells via RAB5/RAB21 endosomes.