PLSCR3 Antikörper

Produktnummer ABIN7075071

Der Kaninchen Polyklonal Anti-PLSCR3-Antikörper wurde für WB validiert. Er ist geeignet, PLSCR3 in Proben von Maus und Ratte zu detektieren.

Kurzübersicht für PLSCR3 Antikörper (ABIN7075071)

Target: PLSCR3 (phospholipid Scramblase 3 (PLSCR3))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLSCR3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PLSCR3 Antikörper

Kreuzreaktivität: Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse PLSCR3

Anwendungsinformationen

Applikationshinweise: WB (M,R) 1: 500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu PLSCR3

Target: PLSCR3 (phospholipid Scramblase 3 (PLSCR3))

Andere Bezeichnung: PLSCR3

Hintergrund: PLSCR3 (phospholipid scramblase 3) may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Members of this family, PLS1 and PLS3 are both substrates of Protein kinase C (PKC) delta and are phosphorylated by PKC-delta during apoptosis. PKC-delta translocates to mitochondria during apoptosis and phosphorylates PLS3. Overexpression of PLS3 in the HEK293 cells enhanced apoptosis induced by UV-irradiation.

Molekulargewicht: 32 kDa

Gen-ID: 70310

NCBI Accession: NP_001161969

UniProt: Q9JIZ9

Pathways: Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis