Der Kaninchen Polyklonal Anti-NCBP2-Antikörper wurde für WB, IHC und IF validiert. Er ist geeignet, NCBP2 in Proben von Human, Maus und Ratte zu detektieren.
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Lagerung
-20 °C
Target
NCBP2
(Nuclear Cap Binding Protein Subunit 2 (NCBP2))
Andere Bezeichnung
NCBP2
Hintergrund
The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein has an RNP domain commonly found in RNA binding proteins, and contains the cap-binding activity. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Multiple transcript variants encoding different isoforms have been found for this gene.