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HLA-DP Antikörper

HLA-DP Reaktivität: Human IF, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7074613
$286.66
Zzgl. Versandkosten $45.00
100 μL
Available
  • Target
    HLA-DP (MHC Class II HLA-DP (HLA-DP))
    Reaktivität
    Human
    Wirt
    Kaninchen
    Klonalität
    Polyklonal
    Applikation
    Immunofluorescence (IF), Immunohistochemistry (IHC)
    Aufreinigung
    Affinity purification
    Immunogen
    KLH conjugated Synthetic peptide corresponding to Human HLA-DP
  • Applikationshinweise
    IHC/IF (H) 1:1200-1:2400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    HLA-DP (MHC Class II HLA-DP (HLA-DP))
    Andere Bezeichnung
    HLA-DP
    Hintergrund
    HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.
    Gen-ID
    3113
    NCBI Accession
    NP_001229453
    UniProt
    P20036
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