HLA-DP Antikörper

Produktnummer ABIN7074613

Dieses Anti-HLA-DP-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HLA-DP in IF und IHC. Geeignet für Human.

Kurzübersicht für HLA-DP Antikörper (ABIN7074613)

Target: HLA-DP (MHC Class II HLA-DP (HLA-DP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HLA-DP Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Immunohistochemistry (IHC)

Produktdetails anti-HLA-DP Antikörper

Aufreinigung: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Human HLA-DP

Anwendungsinformationen

Applikationshinweise: IHC/IF (H) 1:1200-1:2400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu HLA-DP

Target: HLA-DP (MHC Class II HLA-DP (HLA-DP))

Andere Bezeichnung: HLA-DP

Hintergrund: HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.

Gen-ID: 3113

NCBI Accession: NP_001229453

UniProt: P20036