MED8 Antikörper

Produktnummer ABIN7074582

This anti-MED8 antibody (ABIN7074582) is a Rabbit Polyclonal antibody detecting MED8 in WB, IF, IHC. Suitable for Human, Mouse, Rat.

Kurzübersicht für MED8 Antikörper (ABIN7074582)

Target: MED8 (Mediator Complex Subunit 8 (MED8))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MED8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Produktdetails anti-MED8 Antikörper

Kreuzreaktivität: Human, Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse MED8

Anwendungsinformationen

Applikationshinweise: WB (H,M,R) 1:500-1:1000, IHC/IF (M,R) 1:600-1:1200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu MED8

Target: MED8 (Mediator Complex Subunit 8 (MED8))

Andere Bezeichnung: MED8

Hintergrund: MED8, a component of the Mediator complex, is a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. It plays a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins. MED8 has three isoforms with MW 19 kDa, 29 kDa and 33 kDa. And the ubiquitination form will be 38-43 kDa.

Molekulargewicht: 29 kDa

Gen-ID: 80509

NCBI Accession: NP_001277617

UniProt: Q9D7W5

Pathways: Regulation of Lipid Metabolism by PPARalpha