Mannose Receptor Antikörper

Produktnummer ABIN7074550

Der Kaninchen Polyklonal anti-Mannose Receptor Antikörper (ABIN7074550) detektiert spezifisch Mannose Receptor in IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für Mannose Receptor Antikörper (ABIN7074550)

Target: Mannose Receptor (MR)

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Mannose Receptor Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-Mannose Receptor Antikörper

Aufreinigung: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Mannose Receptor

Anwendungsinformationen

Applikationshinweise: IHC/IF (M) 1:400-1:800

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu Mannose Receptor

Target: Mannose Receptor (MR)

Andere Bezeichnung: Mannose Receptor

Hintergrund: CD206, also named as MMR, CLEC13D and MRC1, is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. CD206 has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. CD206 is a 170 kDa transmembrane glycoprotein which contains 5 domains: an amino-terminal cysteine-rich region, a fibronectin type II repeat, a series of eight tandem lectin-like carbohydrate recognition domains (responsible for the recognition of mannose and fucose), a transmembrane domain, and an intracellular carboxy-terminal tail.

Gen-ID: 17533

UniProt: Q61830