Der Kaninchen Polyklonal Anti-MAL2-Antikörper wurde für WB, IF und IHC validiert. Er ist geeignet, MAL2 in Proben von Human, Maus und Ratte zu detektieren.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Target
MAL2
(Mal, T Cell Differentiation Protein 2 (MAL2))
Andere Bezeichnung
MAL2
Hintergrund
MAL2 (mal, T-cell differentiation protein 2) is a 176 amino acid multi-pass membrane protein that is associated with lipid rafts and contains one MARVEL domain. Expressed predominately in liver, kidney and lung, MAL2 functions as a member of the polarized machinery transport system and is required for transcytosis, a transporter pathway used to deliver membrane-bound cargo from perinuclear endosomes to the apical surface in a raft-dependent manner. Differential expression of MAL2 is associated with several cancers, including renal cell carcinoma and childhood leukemia, suggesting a role for MAL2 in tumorigensis.