ISR-alpha Antikörper
Kurzübersicht für ISR-alpha Antikörper (ABIN7074298)
Target
Alle ISR-alpha Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Kreuzreaktivität
- Human, Ratte
-
Aufreinigung
- Affinity purification
-
Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse Insulin Receptor alpha
-
-
-
-
Applikationshinweise
-
IHC: 1: 3000-1: 6000
Human, Mouse, Rat: Human, Mouse, Rat
Positive Tissue: endometrial cancer, esophagus cancer, uterus,small intestine -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- PBS, pH 7.4, 0.02 % sodium azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
-
- ISR-alpha (Insulin Receptor alpha (ISR-alpha))
-
Andere Bezeichnung
- Insulin Receptor alpha
-
Hintergrund
- This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.
-
Gen-ID
- 16337
-
UniProt
- P15208
Target
-