H2-AB1 Antikörper
H2-AB1
Reaktivität: Maus, Ratte
IF, IHC
Wirt: Kaninchen
Polyclonal
unconjugated
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- Target Alle H2-AB1 Produkte
- H2-AB1 (Histocompatibility 2, Class II Antigen A, beta 1 (H2-AB1))
- Reaktivität
- Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
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Konjugat
- Dieser H2-AB1 Antikörper ist unkonjugiert
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Applikation
- Immunofluorescence (IF), Immunohistochemistry (IHC)
- Kreuzreaktivität
- Ratte
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein corresponding to Mouse H2ab1
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anti-Histocompatibility 2, Class II Antigen A, beta 1 (H2-AB1) antibody
H2-AB1 Reaktivität: Maus IF, IHC, WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- IHC/IF (M,R) 1:4000-1:8800
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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- Target
- H2-AB1 (Histocompatibility 2, Class II Antigen A, beta 1 (H2-AB1))
- Andere Bezeichnung
- H2ab1 (H2-AB1 Produkte)
- Synonyme
- AI845868 antikoerper, Abeta antikoerper, H-2Ab antikoerper, H2-Ab antikoerper, I-Abeta antikoerper, IAb antikoerper, Ia-2 antikoerper, Ia2 antikoerper, Rmcs1 antikoerper, histocompatibility 2, class II antigen A, beta 1 antikoerper, H2-Ab1 antikoerper
- Hintergrund
- Atypical histone H2A which replaces conventional H2A during late spermatogenesis and is involved in the replacement of histones to protamine in male germ cells . Core component of nucleosome: nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template . Nucleosomes containing H2AB1 only wrap 130 bp of DNA, compared to 147 bp for classical nucleosomes . In condensing spermatids, the heterodimer between H2AB1 and H2BC1/TH2B is loaded onto the nucleosomes and promotes loading of transition proteins (TNP1 and TNP2) onto the nucleosomes . Inclusion of the H2AB1-H2BC1/TH2B dimer into chromatin opens the nucleosomes, releasing the nucleosomal DNA ends and allowing the invasion of nucleosomes by transition proteins (TNP1 and TNP2) .
- Gen-ID
- 68231
- NCBI Accession
- NP_080903
- UniProt
- Q9CQ70
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