GTF2B Antikörper

Produktnummer ABIN7074034

Dieses Anti-GTF2B-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GTF2B in WB, IHC und IF. Geeignet für Human, Maus und Ratte.

Kurzübersicht für GTF2B Antikörper (ABIN7074034)

Target: GTF2B (General Transcription Factor IIB (GTF2B))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GTF2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-GTF2B Antikörper

Kreuzreaktivität: Human, Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse TFIIB

Anwendungsinformationen

Applikationshinweise: WB (H,M,R) 1: 500-1: 1000, IHC/IF (H,M,R) 1:500-1:1500/1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu GTF2B

Target: GTF2B (General Transcription Factor IIB (GTF2B))

Andere Bezeichnung: TFIIB

Hintergrund: General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II). Involved in the pre-initiation complex (PIC) formation and Pol II recruitment at promoter DNA .Together with the TATA box-bound TBP forms the core initiation complex and provides a bridge between TBP and the Pol II-TFIIF complex .Released from the PIC early following the onset of transcription during the initiation and elongation transition and reassociates with TBP during the next transcription cycle . Associates with chromatin to core promoter- specific regions .Binds to two distinct DNA core promoter consensus sequence elements in a TBP-independent manner,Modulates transcription start site selection . Exhibits also autoacetyltransferase activity that contributes to the activated transcription .

Molekulargewicht: 35 kDa

Gen-ID: 229906

NCBI Accession: NP_663521

UniProt: P62915