EEA1 Antikörper

Produktnummer ABIN7073795

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch EEA1 in IHC und IF. Er zeigt eine Reaktivität gegenüber Maus und Ratte.

Kurzübersicht für EEA1 Antikörper (ABIN7073795)

Target: EEA1 (Early Endosome Antigen 1 (EEA1))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EEA1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-EEA1 Antikörper

Kreuzreaktivität: Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse EEA1

Anwendungsinformationen

Applikationshinweise: IHC/IF (M,R) 1:2000-1:5000/1:1000-1:1500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu EEA1

Target: EEA1 (Early Endosome Antigen 1 (EEA1))

Andere Bezeichnung: EEA1

Hintergrund: Early endosomes are cytoplasmic compartments that function in receiving and sorting endocytosed proteins for vesicular transport. EEA1 (early endosome antigen 1) is a peripheral membrane protein that co-localizes with the transferrin receptor and Rab5 on early endosomes. EEA1 contains a calmodulin-binding IQ motif and cysteine rich finger motif necessary for its specific localization to the early endosomes. EEA1 has sequence homology to several yeast proteins that have been implicated in membrane trafficking, including Vps27, Fab1 and Vac1. Evidence suggests a possible role for EEA1 in mediating the regulatory effects of 3'-phosphoinositides on membrane trafficking.

Gen-ID: 216238

NCBI Accession: NP_001001932

UniProt: Q8BL66

Pathways: Toll-Like Receptors Cascades