CYB561 Antikörper
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- Target Alle CYB561 Antikörper anzeigen
- CYB561 (Cytochrome B-561 (CYB561))
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Reaktivität
- Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CYB561 Antikörper ist unkonjugiert
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Applikation
- Immunofluorescence (IF), Immunohistochemistry (IHC)
- Kreuzreaktivität
- Ratte
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein corresponding to Mouse Pyruvate Dehydrogenase E2
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anti-Cytochrome B-561 (CYB561) antibody
CYB561 Reaktivität: Human, Maus WB, IP, ICC Wirt: Maus Monoclonal unconjugated
anti-Cytochrome B-561 (CYB561) (AA 144-193) antibodyCYB561 Reaktivität: Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Hund, Pferd, Kaninchen, Schaf, Schwein, Hamster WB Wirt: Kaninchen Polyclonal unconjugated
anti-Cytochrome B-561 (CYB561) (C-Term) antibodyCYB561 Reaktivität: Human, Maus, Ratte, Affe, Xenopus laevis WB Wirt: Kaninchen Polyclonal unconjugated
anti-Cytochrome B-561 (CYB561) (AA 72-121) antibodyCYB561 Reaktivität: Human, Meerschweinchen, Affe, Fledermaus WB Wirt: Kaninchen Polyclonal unconjugated
anti-Cytochrome B-561 (CYB561) antibodyCYB561 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Cytochrome B-561 (CYB561) (Middle Region) antibodyCYB561 Reaktivität: Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Hund, Pferd, Kaninchen, Schaf, Schwein WB Wirt: Kaninchen Polyclonal unconjugated
anti-Cytochrome B-561 (CYB561) (N-Term) antibodyCYB561 Reaktivität: Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Hund, Pferd, Kaninchen, Schaf WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- IHC/IF (R) 1:500-1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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- Target
- CYB561 (Cytochrome B-561 (CYB561))
- Andere Bezeichnung
- Pyruvate Dehydrogenase E2 (CYB561 Produkte)
- Synonyme
- CYB561A1 antikoerper, FRRS2 antikoerper, ECK1410 antikoerper, JW5224 antikoerper, MGC69260 antikoerper, zgc:193680 antikoerper, zgc:193701 antikoerper, ACYB-1 antikoerper, MBB18.18 antikoerper, MBB18_18 antikoerper, cytochrome B561-1 antikoerper, xcyt antikoerper, cytochrome b561 antikoerper, cytochrome b-561 antikoerper, cytochrome B561-1 antikoerper, cytochrome b561 L homeolog antikoerper, CYB561 antikoerper, cytb561 antikoerper, cybB antikoerper, LOC5576849 antikoerper, LOC5576850 antikoerper, Cyb561 antikoerper, cyb561 antikoerper, CYB-1 antikoerper, cyb561.L antikoerper, LOC100347599 antikoerper
- Hintergrund
- This gene encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A. Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95 % of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC enventually leads to cirrhosis and liver failure.
- Gen-ID
- 235339
- UniProt
- Q8BMF4
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