C17orf37 Antikörper

Produktnummer ABIN7073498

Produktdetails anti-C17orf37 Antikörper

Target: C17orf37 (Chromosome 17 Open Reading Frame 37 (C17orf37))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C17orf37 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse XTP4

Anwendungsinformationen

Applikationshinweise: WB (M,R) 1:200-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu C17orf37

Target: C17orf37 (Chromosome 17 Open Reading Frame 37 (C17orf37))

Andere Bezeichnung: XTP4 (C17orf37 Produkte)

Synonyme: C17orf37 antikoerper, C35 antikoerper, ORB3 antikoerper, RDX12 antikoerper, XTP4 antikoerper, C19H17orf37 antikoerper, 1810046J19Rik antikoerper, AI463380 antikoerper, Rdx12 antikoerper, migration and invasion enhancer 1 antikoerper, migration and invasion enhancer 1 S homeolog antikoerper, mien1 antikoerper, mien1.S antikoerper, MIEN1 antikoerper, Mien1 antikoerper

Hintergrund: During the past decade, the role of the ERBB2(neu/HER2) oncogene as an important predictor of patient outcome and response to various therapies in breast cancer has been clearly established. The C35 (C17orf37) is a novel tumor biomarker abundantly expressed in breast cancer. Identification of shared tumor-specific targets is useful in developing broadly applicable therapies. The C35 gene is located on chromosome 17q12, 505nucleotides from the 3' end of the ERBB2oncogene, the antigenic target for trastuzumab(Herceptin) therapy. The chromosomal arrangement of the genes encoding C35 andERBB2 is tail to tail.

Molekulargewicht: 12 kDa

Gen-ID: 103742

NCBI Accession: NP_079835

UniProt: Q9CQ86

Pathways: Cell RedoxHomeostasis