CD5L Antikörper

Produktnummer ABIN7073398

Dieses Anti-CD5L-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CD5L in WB. Geeignet für Ratte.

Kurzübersicht für CD5L Antikörper (ABIN7073398)

Target: CD5L (CD5 Molecule-Like (CD5L))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD5L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CD5L Antikörper

Kreuzreaktivität: Ratte

Aufreinigung: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse CD5L/CT-2

Anwendungsinformationen

Applikationshinweise: WB (R) 1:700-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu CD5L

Target: CD5L (CD5 Molecule-Like (CD5L))

Andere Bezeichnung: CD5L/CT-2

Hintergrund: CD5L is a member of the scavenger receptor cysteine-rich domain superfamily (SRCR-SF) initially identified as an inducible cell surface ligand of CD5. It was shown that CD5L functions in the thymus as the inducer of resistance to apoptosis within CD4+/CD8+ thymocytes and as the supporter of the viability of these cells before thymic selection. CD5L was also shown to support macrophage survival and enhance their phagocytic function. More recent experiments using recombinant CD5L significantly inhibited apoptosis of NKT and T cells obtained from C. parvum-stimulated livers in vitro, suggesting that CD5L functions to induce resistance to apoptosis in these cells and supports host defense against inflammation during infection. Expressed in spleen, lymph node, thymus, bone marrow, and fetal liver, but not in non-lymphoid tissues.

Molekulargewicht: 46 kDa

Gen-ID: 11801

NCBI Accession: NP_033820

UniProt: Q9QWK4