Cathepsin L2 Antikörper

Produktnummer ABIN7073348

Produktdetails anti-Cathepsin L2 Antikörper

Target: Cathepsin L2 (CTSL2)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cathepsin L2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Human Cathepsin V

Anwendungsinformationen

Applikationshinweise: IHC/IF (H,M,R) 1:1000-1:2000/1:300-1:600

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu Cathepsin L2

Target: Cathepsin L2 (CTSL2)

Andere Bezeichnung: Cathepsin V (CTSL2 Produkte)

Hintergrund: Cathepsin V is a lysosomal cysteine protease which has an important role in corneal physiology.Cathepsin V was found to be differentially expressed in relation to pigmentary skin backgrounds, and was about 7.5-folds higher in keratinocytes from lightly pigmented, relative to darkly pigmented skins. It is expressed in primary keratinocytes, melanocytes, and HaCaT keratinocytes, but not in primary fibroblasts. The purified cathepsin L2 was a high molecular weight proteinase of about 78 kDa, but it was unstable to SDS and reducing conditions, which dissociated parts of the proteinase into 66 kDa, 31 kDa and 26 kDa fragments(Food Chemistry,Volume11,Issue4,879-886) and it can form a complex of 70 kDa with an unidentified subunit.

Gen-ID: 1515

NCBI Accession: NP_001188504

UniProt: O60911

Pathways: Toll-Like Receptors Cascades