BEND3 Antikörper
Kurzübersicht für BEND3 Antikörper (ABIN7073204)
Target
Alle BEND3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Human, Ratte
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant protein corresponding to Mouse BEND3
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Applikationshinweise
- WB (H,M,R) 1:500-1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- BEND3 (BEN Domain Containing 3 (BEND3))
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Andere Bezeichnung
- BEND3
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Hintergrund
- The BEND3 is a transcriptional repressor which associates with the NoRC (nucleolar remodeling complex) complex and plays a key role in repressing rDNA transcription. The sumoylated form modulates the stability of the NoRC complex component BAZ2A/TIP5 by controlling its USP21-mediated deubiquitination. Binds to unmethylated major satellite DNA and is involved in the recruitment of the Polycomb repressive complex 2 (PRC2) to major satellites.
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Molekulargewicht
- 100 kDa
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Gen-ID
- 331623
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NCBI Accession
- NP_950193
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UniProt
- Q6PAL0
Target
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