Basonuclin 1 Antikörper

Produktnummer ABIN7073188

Dieses Anti-Basonuclin 1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Basonuclin 1 in WB. Geeignet für Human, Maus und Ratte.

Kurzübersicht für Basonuclin 1 Antikörper (ABIN7073188)

Target: Basonuclin 1 (BNC1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Basonuclin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Basonuclin 1 Antikörper

Kreuzreaktivität: Human, Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse BNC1/BNC

Anwendungsinformationen

Applikationshinweise: WB (H,M,R) 1:250-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu Basonuclin 1

Target: Basonuclin 1 (BNC1)

Andere Bezeichnung: BNC1/BNC

Hintergrund: The zinc finger protein, basonuclin, is a putative rDNA transcription factor with highly restricted tissue distribution. Basonuclin is abundantly expressed in keratinocytes of the basal layer of the epidermis, the outer sheath of hair follicles and in the germ cells of the testis and ovary. In the epidermis, basonuclin, which is mainly localized to the cytoplasm, translocates to basal cell nuclei during different stages of keratinocyte growth. Basonuclin may enhance rRNA synthesis by elevating transcription from an rDNA promoter and inhibiting RNA polymerase I transcription through its zinc finger domain. Therefore, basonuclin may be a cell-type-specific transcription factor for rDNA transcription.

Molekulargewicht: 107 kDa

UniProt: O35914