ABCC6 Antikörper

Produktnummer ABIN7073149

Der Kaninchen Polyklonal anti-ABCC6 Antikörper (ABIN7073149) detektiert spezifisch ABCC6 in IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Maus und Ratte.

Kurzübersicht für ABCC6 Antikörper (ABIN7073149)

Target: ABCC6 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 6 (ABCC6))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABCC6 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-ABCC6 Antikörper

Kreuzreaktivität: Ratte

Aufreinigung: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse MRP6/ARA

Anwendungsinformationen

Applikationshinweise: IHC/IF (M,R) 1:1000-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu ABCC6

Target: ABCC6 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 6 (ABCC6))

Andere Bezeichnung: MRP6/ARA

Hintergrund: The ATP-binding cassette transporter 6 (ABCC6) gene, also named as MRP6, is a cellular transmembrane protein transporter and belongs to ATP-binding cassette (ABC) family. ABCC6 is an ATP-dependent transporter contains two ATP-binding domains. It is mainly found in the liver, the proximal tubules of the kidneys and the intestines. ABCC6 is involved in a pathway of extracellular nucleotide metabolism and the regulation of tissue calcification. Mutations of ABCC6 leads to pseudoxanthoma elasticum (PXE) which is a rare autosomal recessive disorder. Mutations of ABCC6 can also lead generalized arterial calcification of infancy-2 (GACI2). 27848-1-AP detects two isoforms of ABCC6 protein around 165 kDa and 96 kDa in SDS-PAGE.

Gen-ID: 27421

NCBI Accession: NP_061265

UniProt: Q9R1S7