UCHL1 Antikörper (AA 35-140)

Produktnummer ABIN704396

Es sind 5+ Publikationen für dieses Produkt verfügbar. Der Kaninchen Polyklonal anti-UCHL1 Antikörper wird verwendet zum Nachweis von UCHL1 in Proben von Human. Er wurde validiert für WB, IHC (p), IF (cc), IF (p) und IHC (fro).

Kurzübersicht für UCHL1 Antikörper (AA 35-140) (ABIN704396)

Target: UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UCHL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-UCHL1 Antikörper

Bindungsspezifität: AA 35-140

Verwendungszweck: PGP9.5 Polyclonal Antibody

Kreuzreaktivität: Rind (Kuh), Human, Maus, Ratte

Homologie: Pig,Horse,GuineaPig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PGP9.5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:300-5000),

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-UCHL1 Antikörper (ABIN704396)

Sunardi, Ito, Sato, Uesaka, Iwasaki, Enomoto: "A Single RET Mutation in Hirschsprung Disease Induces Intestinal Aganglionosis Via a Dominant-Negative Mechanism." in: Cellular and molecular gastroenterology and hepatology, Vol. 15, Issue 6, pp. 1505-1524, (2023) (PubMed).

Zheng, Zhu, Mu, Wu, Song, Zhai, Peng, Li, Hua: "CD49f promotes proliferation of male dairy goat germline stem cells." in: Cell proliferation, Vol. 49, Issue 1, pp. 27-35, (2016) (PubMed).

Li, Zhuang, Wu, Niu, Zhang, Li, Wei, Li, Hua: "Bovine male germline stem-like cells cultured in serum- and feeder-free medium." in: Cytotechnology, Vol. 68, Issue 5, pp. 2145-57, (2016) (PubMed).

Deng, Chen, Wang, Zhang, Tang, Li, Wang, Cheng, Jin, Li, Zhang, Yu, Lian, Liu, Liu: "Melatonin promotes development of haploid germ cells from early developing spermatogenic cells of Suffolk sheep under in vitro condition." in: Journal of pineal research, Vol. 60, Issue 4, pp. 435-47, (2016) (PubMed).

Zheng, Zhai, Li, Ma, Zhu, Du, Li, Hua: "The Modification of Tet1 in Male Germline Stem Cells and Interact with PCNA, HDAC1 to promote their Self-renewal and Proliferation." in: Scientific reports, Vol. 6, pp. 37414, (2016) (PubMed).

Details zu UCHL1

Target: UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))

Andere Bezeichnung: UCHL1/PGP9.5

Hintergrund:

Synonyms: NDGOA, PARK5, PGP95, PGP9.5, Uch-L1, HEL-117, PGP 9.5, Ubiquitin carboxyl-terminal hydrolase isozyme L1, Neuron cytoplasmic protein 9.5, Ubiquitin thioesterase L1, UCHL1

Background: Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.

Gen-ID: 7345

UniProt: P09936

Pathways: Feeding Behaviour