Rekombinanter beta 2 Adrenergic Receptor Antikörper

Produktnummer ABIN7072670

Der Maus Monoklonal anti-beta 2 Adrenergic Receptor Antikörper wird verwendet zum Nachweis von beta 2 Adrenergic Receptor in Proben von Human. Er wurde validiert für WB, ELISA, IF und IP.

Kurzübersicht für Rekombinanter beta 2 Adrenergic Receptor Antikörper (ABIN7072670)

Target: beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser beta 2 Adrenergic Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Klon: 13D6

Produktdetails anti-beta 2 Adrenergic Receptor Antikörper

Verwendungszweck: Anti-Beta 2 adrenergic receptor [13D6], Mouse IgG1, kappa

Spezifität:

13D6 antibody recognizes human beta-2 adrenergic receptor. It was reported that this antibody recognizes extracellualr domains of the receptor (Han et al., 2012). Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds adrenaline with far grater affinity than noradrenaline.

Application Notes original Clone: This antibody is recommended for the identification and analysis of the β2-adrenergic receptor. For instance, tt was used to immunostain vascular smooth muscle cells (VSMCs) against beta-2-adrenergic receptor to determine the fate of beta-2ARs ubiquitinated in a carvedilol responsive manner (Han et al., 2012). Furthermore, the antibody was utilized in the quantification of the surface level of β-2ARs via ELISA (Han et al., 2012).

Aufreinigung: Protein A affinity purified

Immunogen: This antibody was raised by immunizing mice with beta-2 adrenergic receptor.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

OriginalSpeciesName: Mouse

OriginalFormat: IgG1

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu beta 2 Adrenergic Receptor

Target: beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

Andere Bezeichnung: Beta 2 adrenergic receptor

Hintergrund: R11E1, Beta-2 adrenergic receptor, Beta-2 adrenoreceptor, Beta-2 adrenoceptor, β-2 adrenergic receptor, β-2 adrenoreceptor, β-2 adrenoceptor, β2AR, β2-AR, I3D6

UniProt: P07550

Pathways: cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation