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Rekombinanter CD81 Antikörper

Dieses Kaninchen Chimeric-Antikörper erkennt spezifisch CD81 in FACS, WB, IHC und IF. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN7072642

Kurzübersicht für Rekombinanter CD81 Antikörper (ABIN7072642)

Target

Alle CD81 Antikörper anzeigen
CD81

Antikörpertyp

Recombinant Antibody

Reaktivität

  • 208
  • 142
  • 80
  • 25
  • 25
  • 25
  • 18
  • 17
  • 9
  • 9
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 119
  • 92
  • 41
  • 11
  • 3
  • 3
  • 1
  • 1
Kaninchen

Klonalität

  • 208
  • 56
  • 3
Chimeric

Konjugat

  • 111
  • 22
  • 19
  • 18
  • 10
  • 7
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CD81 Antikörper ist unkonjugiert

Applikation

  • 197
  • 104
  • 84
  • 52
  • 48
  • 41
  • 35
  • 30
  • 30
  • 26
  • 22
  • 14
  • 14
  • 13
  • 6
  • 5
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Klon

1-3-3-22
  • Verwendungszweck

    Anti-CD81 [1.3.3.22], Rabbit IgG, kappa

    Spezifität

    1.3.3.22 antibody recognizes CD81. Human CD81 is a member of the tetraspanin family of leukocyte cell surface molecules which are involved in signal transduction, cell-cell adhesion and cellular activation. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. It is present on a wide variety of leukocytes.

    Kreuzreaktivität

    Maus, Ratte

    Produktmerkmale

    Original Species of Ab: Mouse

    Original Format of Ab: IgG1

    Aufreinigung

    Protein A affinity purified

    Immunogen

    This antibody was raised by immunizing mice with a B-Cell line derived from a Burkitt lymphoma.

    Isotyp

    IgG kappa
  • Applikationshinweise

    Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas and thus 1.3.3.22 can be used as a research antibody in the studies on lymphoma therapeutics. This antibody is also recommended in the detection and analysis of CD81 via various methods. For instance, 1.3.3.22 antibody was used in the identification of CD81 in human arteries by immunohistochemistry (Rohlena et al., 2009). 1.3.3.22 was also successfully utilized during flow cytometric detection of CD81 on KM3 cells (Higginbottom et al., 2000).

    Kommentare

    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1 mg/mL

    Buffer

    PBS with 0.02 % Proclin 300.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Target

    CD81

    Andere Bezeichnung

    CD81

    Hintergrund

    TSPAN-28, Tetraspanin-28, TSPAN28, CD81 antigen, 26 kDa cell surface protein TAPA-1, Target of the antiproliferative antibody 1, TAPA-1, TAPA1

    UniProt

    P60033

    Pathways

    Inositol Metabolic Process, Hepatitis C
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