Rekombinanter CD63 Antikörper
Kurzübersicht für Rekombinanter CD63 Antikörper (ABIN7072636)
Target
Alle CD63 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
 - Anti-CD63 [NK-1-C3], Rabbit IgG, kappa
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Spezifität
 - This antibody recognizes CD63. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation and plays a role in the activation of cellular signaling cascades.
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Kreuzreaktivität
 - Maus
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Produktmerkmale
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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Aufreinigung
 - Protein A affinity purified
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Immunogen
 - This antibody was raised by immunizing BALB/c mice with a plasma membrane preparation of the human melanoma MeWo cells.
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Isotyp
 - IgG kappa
 
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Applikationshinweise
 - The antibody NK-1-C3 has been widely used for the detection and analysis of CD63 via various methods. For instance, NK-1-C3 (NK1/C3) proved successfull in labelling CD63 in multiple tissues, for example, when localizing CD63 in murine retinal pigment epithelium (RPE)/choroid tissue (Wang et al., 2009). Similarly, this antibody was used to detect CD63 on melanoma cells via immunofluorescence staining (Khazen et al., 2016).
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Kommentare
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
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Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Konzentration
 - 1 mg/mL
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Buffer
 - PBS with 0.02 % Proclin 300.
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Konservierungsmittel
 - ProClin
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Vorsichtsmaßnahmen
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
 - 4 °C,-20 °C
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Informationen zur Lagerung
 - Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
 
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- CD63
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Andere Bezeichnung
 - CD63
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Hintergrund
 - Granulophysin, LAMP-3, Tetraspanin-30, Tspan-30, Lysosomal-associated membrane protein 3, Melanoma-associated antigen ME491, OMA81H, Ocular melanoma-associated antigen, CD63 antigen, NK1/C3, NKI/C3, NK-1.C3, NK1C3
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UniProt
 - P08962
 
Target
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