Rekombinanter CD37 Antikörper
Kurzübersicht für Rekombinanter CD37 Antikörper (ABIN7072629)
Target
Alle CD37 (TSPAN26) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-CD37 [IPO-24 (ZC37-24)], Mouse IgG2b, kappa
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Spezifität
- This antibody recognizes CD37, which is a cell surface protein, present mostly on mature B cells and B cell malignancies.
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Produktmerkmale
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Original Species of Ab: Mouse
Original Format of Ab: IgG2b
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Aufreinigung
- Protein A affinity purified
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Immunogen
- This antibody was raised by immunizing mice with spleen cells of a patient with hairy cell leukemia.
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Isotyp
- IgG2b kappa
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Applikationshinweise
- This antibody is recommended for the analysis and detection of B cells and their malignancies as CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies, such as B-cell chronic lymphocytic leukemia (B-CLL), hairy cell leukemia (HCL), and all types of B-cell non-Hodgkin's lymphoma (B-NHL). Consequently, this antibody might be useful for the treatment of B cell malignancies and autoimmune and inflammatory diseases that involve B cells in their pathology. Finally, IPO-24 antibody, might be used to identify CD37 via various techniques. For instance, it was used to evaluate CD37 expression in mantle cell lymphoma samples via immunohistochemistry (Leshchenko et al., 2010).
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
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Andere Bezeichnung
- CD37
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Hintergrund
- Tetraspanin-26, Leukocyte antigen CD37, tetraspanin, Tspan-26, Gp52-40
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UniProt
- P11049
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Pathways
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
Target
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