Rekombinanter Fc epsilon R (N-Term) Antikörper

Produktnummer ABIN7072586

Produktdetails

Target: Fc epsilon R

Antikörpertyp: Recombinant Antibody

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Unkonjugiert

Applikation: Flow Cytometry (FACS), Blocking Reagent (BR)

Verwendungszweck: Anti-Fc epsilon R [IB10], Rabbit IgG, kappa

Spezifität: This antibody binds to human Fc epsilon receptor and competes with IgE binding.

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Aufreinigung: Protein A affinity purified

Immunogen: Recombinant human protein, N-terminus.

Klon: IB10

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: IB10 competes with IgE for binding to human FceRIa, consequently, its binding to mast cells and basophils is decreased when IgE concentration is high, but it does block IgE binding to these cells. IB10 and IE7 (Ab01397) do not crossblock each other's binding.

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Antigendetails

Target: Fc epsilon R

Hintergrund: FceRI, IgE receptor

UniProt: P30273