Rekombinanter Interleukin 17a Antikörper

Produktnummer ABIN7072560

Dieses Anti-Interleukin 17a-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Interleukin 17a in ELISA und BP. Geeignet für Maus.

Kurzübersicht für Rekombinanter Interleukin 17a Antikörper (ABIN7072560)

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Antikörpertyp: Recombinant Antibody

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Interleukin 17a Antikörper ist unkonjugiert

Applikation: ELISA, Blocking Peptide (BP)

Klon: MM17F3

Produktdetails anti-Interleukin 17a Antikörper

Verwendungszweck: Anti-IL-17A [MM17F3], Mouse IgG1, kappa

Spezifität: This antibody is highly specific for murine IL-17A, in ELISA analysis, no cross-reactivity with IL-17B, IL-17C, IL-17D, IL-17E or IL-17F was observed.

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Aufreinigung: Protein A affinity purified

Immunogen: This antibody was raised by immunising C57Bl/6 mice with IL-17A cross-linked to ovalbumin to generate a highly immunogenic complex.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: The specificity of this antibody has been confirmed in ELISA analysis (Uyttenhove et al, 2006). This antibody inhibits IL-17A-induced IL-6 production by a Cl1D fibroblastic cell line in vitro (Uyttenhove et al, 2006). This antibody has been shown to prevent experimental autoimmune encephalomyelitis (EAE) disease development in vivo (Uyttenhove et al, 2006), as well as protecting C57Bl/6 mice from myelin oligdendrocyte glycoprotein (MOG)-induced EAE (Uyttenhove et al, 2007). Additionally, administration of this antibody inhibits collagen-induced arthritis (CIA) in IFN-γ receptor knockout mice (Kelchtermans et al, 2009).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu Interleukin 17a

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Andere Bezeichnung: IL-17A

Hintergrund: Interleukin-17A, IL17A, Cytotoxic T-lymphocyte-associated antigen 8, CTLA-8

UniProt: Q62386