Rekombinanter RHD Antikörper
Kurzübersicht für Rekombinanter RHD Antikörper (ABIN7072535)
Target
Alle RHD Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
 - Anti-Rhesus D antigen [D7C2], Rabbit IgG, lambda
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Produktmerkmale
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Original Species of Ab: Human
Original Format of Ab: IgM
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Aufreinigung
 - Protein A affinity purified
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Immunogen
 - A Rh- volunteer blood donor (r/r) was injected with 5ml of Rh+ erythrocytes (R1/r) and the peripheral lymphocytes were isolated and transformed with 1 ml of culture supernatant of the EBV marmoset B96-8 cell line.
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Isotyp
 - IgG lambda
 
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Applikationshinweise
 - FC confirmed the binding of D7C2 to Rh D+ red cells in artifical mixtures (Edelman et al, 1997). The ADCC of D7C2 showed a percentage of 93 % lysis (Edelman et al, 1997). D7C2 has been expressed recombinantly using a baculovirus-insect cell expression system (Edelman et al, 1997).
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Kommentare
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This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgM format, for improved compatibility with existing reagents, assays and techniques.
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Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Konzentration
 - 1 mg/mL
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Buffer
 - PBS with 0.02 % Proclin 300.
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Konservierungsmittel
 - ProClin
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Vorsichtsmaßnahmen
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
 - 4 °C,-20 °C
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Informationen zur Lagerung
 - Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
 
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- RHD (Rh Blood Group, D Antigen (RHD))
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Andere Bezeichnung
 - Rhesus D antigen
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Hintergrund
 - CD240D, RHXIII, Rh polypeptide 2, RhPII
 
Target
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