Rekombinanter CLEC4A Antikörper

Produktnummer ABIN7072449

Dieses Anti-CLEC4A-Antikörper ist ein Kaninchen Chimeric-Antikörper zur Detektion von CLEC4A in FACS. Geeignet für Human.

Kurzübersicht für Rekombinanter CLEC4A Antikörper (ABIN7072449)

Target: CLEC4A (C-Type Lectin Domain Family 4, Member A (CLEC4A))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser CLEC4A Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: 9E8

Produktdetails anti-CLEC4A Antikörper

Verwendungszweck: Anti-DCIR [9E8], Rabbit IgG, kappa

Spezifität: This antibody is specific for human DCIR, which is expressed by monocytes, B cells, neutrophils, granulocytes and dendritic cells.

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Aufreinigung: Protein A affinity purified

Immunogen: This antibody was raised by immunising BALB/c mice with a dendritic cell immunoreceptor ectodomain-human Fc fusion protein.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: This antibody has been used in flow cytometric analysis of DCIR expression by peripheral blood mononuclear cells (Klechevsky et al, 2010). A recombinant humanised form of this antibody fused to protein antigens is under investigation as an antigen-targeting vaccine (Flamar et al, 2012), and has been shown to trigger antigen-specific CD8+ T cell immunity.

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu CLEC4A

Target: CLEC4A (C-Type Lectin Domain Family 4, Member A (CLEC4A))

Andere Bezeichnung: DCIR

Hintergrund: CD367, Clec4A, C-type lectin domain family 4 member A, LLIR, CLECSF6, C-type lectin DDB27, C-type lectin superfamily member 6, Dendritic cell immunoreceptor, Lectin-like immunoreceptor