Rekombinanter CD81 Antikörper

Produktnummer ABIN7072377

Dieses Anti-CD81-Antikörper ist ein Kaninchen Chimeric-Antikörper zur Detektion von CD81 in FACS, WB, ELISA, IP, IF, Func, IHC (p) und ICC. Geeignet für Human, Schaf, Ziege und Schimpanse.

Kurzübersicht für Rekombinanter CD81 Antikörper (ABIN7072377)

Target: CD81

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Schaf, Ziege, Schimpanse

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser CD81 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Functional Studies (Func), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Klon: 1D6

Produktdetails anti-CD81 Antikörper

Verwendungszweck: Anti-CD81 [1D6], Rabbit IgG, kappa

Spezifität: This antibody is specific for human CD81, which is expressed on most tissues with the exception of red blood cells and platelets.

Kreuzreaktivität: Schimpanse, Ziege, Schaf

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Aufreinigung: Protein A affinity purified

Immunogen: This antibody was produced by immunizing mice with 5A6-aggregated OCI-LY8 B cells.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: This antibody is a strong inducer of homotypic adhesion in hematolymphoid cells (Levy, 1998). This antibody also has an anti-proliferative effect, and is able to induce growth inhibition of B cell lines. Triggering of CD81 by this antibody induces a significant upregulation of the constituitive release of TNF-α by JY cells, an Eptsein-Barr virus-positive B lymphoblastoid cell line (Altomonte, 1995).

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu CD81

Target: CD81

Andere Bezeichnung: CD81

Hintergrund: Tetraspanin-28, TAPA-1, Target of the Antiproliferative Antibody 1, Tspan-28

UniProt: P60033

Pathways: Inositol Metabolic Process, Hepatitis C